diff --git a/requirements.txt b/requirements.txt
index f3c61e790ba0d157126c5d615bfa49bf35dd34f4..1602750fded84a4ea25a93875b686c90ecff3d7b 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -11,6 +11,8 @@ packaging==16.8
 pycparser==2.17
 pyOpenSSL==17.0.0
 pyparsing==2.2.0
+pypiwin32==219; sys_platform == 'win32' and python_version < '3.6'
+pypiwin32==220; sys_platform == 'win32' and python_version >= '3.6'
 requests==2.14.2
 six==1.10.0
 websocket-client==0.40.0
diff --git a/setup.py b/setup.py
index 468245101de7571fad734592053fd5e7288a312a..b628f4a878e5fec00531380ad964ea0e2a9767dc 100644
--- a/setup.py
+++ b/setup.py
@@ -26,9 +26,6 @@ requirements = [
     'docker-pycreds >= 0.2.1'
 ]
 
-if sys.platform == 'win32':
-    requirements.append('pypiwin32 >= 219')
-
 extras_require = {
     ':python_version < "3.5"': 'backports.ssl_match_hostname >= 3.5',
     # While not imported explicitly, the ipaddress module is required for
@@ -36,6 +33,12 @@ extras_require = {
     # ServerAltname: https://pypi.python.org/pypi/backports.ssl_match_hostname
     ':python_version < "3.3"': 'ipaddress >= 1.0.16',
 
+    # win32 APIs if on Windows (required for npipe support)
+    # Python 3.6 is only compatible with v220 ; Python < 3.5 is not supported
+    # on v220 ; ALL versions are broken for v222 (as of 2018-01-26)
+    ':sys_platform == "win32" and python_version < "3.6"': 'pypiwin32==219',
+    ':sys_platform == "win32" and python_version >= "3.6"': 'pypiwin32==220',
+
     # If using docker-py over TLS, highly recommend this option is
     # pip-installed or pinned.
 
diff --git a/win32-requirements.txt b/win32-requirements.txt
index 6db52a50b4af23220750ed6fbd819693a88e186a..bc04b4960a7552e403b95f80dcce0b9b4aedc34c 100644
--- a/win32-requirements.txt
+++ b/win32-requirements.txt
@@ -1,2 +1 @@
 -r requirements.txt
-pypiwin32>=219